I had to modify Wire initialization in the AdaFruit library but as you can see I was able to use AdaFruit's awesome graphics library on the ESP8266.
UPDATE 6/3/2015:
In ESP8266's Wire library, I discovered a way to set which GPIO pins should be used for I2C. It spat out a warning about deprecated call, but it works and I no longer had to modify any libraries. Schema and code is available on my Hackaday.io page: https://hackaday.io/post/18891